top of page
Pre-Meeting Workshops
Friday, October 6th, 2023
  • BOLD fMRI Hands-on Workshop 
  • Member Initiated Mini-Symposium | Cerebrovascular Reactivity
  • AI Workshop
  • Perfusion Imaging Workshop

Member Initiated Mini-Symposia

Cerebrovascular Reactivity Workshop: A New Clinical “Brain Stress Test”


Cerebrovascular reserve is difficult to assess in patients with cerebrovascular steno-occlusive disease.  CT and MRI perfusion techniques measure resting blood flow but become increasingly less reliable as the degree and number of stenoses increase.  Measures of adequate baseline blood flow do not account for a possible shortfall in recruitable blood flow due to a drop in supply or an increased metabolic demand. Visualization of the temporal filling patterns with angiography may give some indication of the presence of collateral blood flow, but not its physiologic adequacy.


With the heart, the Cardiac Stress Test, is the bedrock in the assessment of vascular reserve in the prediction of MI.  Similarly, in the brain, hemodynamic reserve is the strongest known indicator of risk of stroke.  As such, we have developed a “Brain Stress Test” and studied more than 3000 patients with cerebrovascular disease over 20 years.  This test provides key data for:

  • informing patient management decisions

  • following the evolution of a known vascular lesions over time

  • determining the effectiveness of a therapeutic intervention. 


Educational Objectives

Learn optimal performance and interpretation of the “brain stress test” via presentations with interactive question and answer, live demonstration, hands-on practice that includes control of automated gas blender, data analysis, and image interpretation.


Target Audience
Neuroradiologists, neurosurgeons, neurologists, MR scientists


  • Joseph Fisher, MD, Toronto General Hospital and the University of Toronto, Toronto, ON

  • David Mikulis, MD, Toronto Western Hospital and the University of Toronto, Toronto, ON

  • Prasanna Vibhute, MD, Mayo Clinic Jacksonville, FL

  • Andrea Para. MD, MSc, Toronto Western Hospital and the University of Toronto, Toronto, ON




1:00 – 2:30     Presentations:


1:00     Welcome / Introduction

1:05     What is a “Brain Stress Test” and why do I need it? 

1:30     Breath Hold CVR Mapping - Don’t Hold Your Breath! The Good, The Bad, The Ugly

1:50     Measuring CVR: Is “Quick and Dirty” Good Enough?

2:05     Clinical Utility of the “Brain Stress Test”: Case Examples


2:30 - 3:00      Coffee Break


3:00 – 5:00     Small Group Learning Stations (30-minute rotations):


1. Development of a standardized CVR test for clinical utility

2. Hands on device and software use

3. CVR report and expanded case reporting

4. Discussion: Clinical Value for Patient Management

BOLD fMRI Workshop

About This Workshop

Each year a BOLD fMRI hands-on workshop is offered in conjunction with the Annual Meeting. 

This workshop will provide a didactic review of clinical fMRI and practical step-by-step post-processing and data presentation of BOLD fMRI of both task-based language and sensory-motor cortex and resting state studies using MATLAB with SPM12 and CONN toolbox software.

Program from 2023 

Course Directors: Scott H. Faro, M.D., FASFNR AND Feroze B. Mohamed, Ph.D., FASFNR


7:30 – 8:25 AM Registration and Continental Breakfast for Registrants



8:25 – 8:30.      Welcome
                          Scott H. Faro, MD, FASFNR

8:30 – 9:15        Introduction to BOLD, Paradigm Design, and SPM
                          Chris Conklin, PhD


9:15 – 9:45        Introduction to General Linear Model for Task Based BOLD fMRI Analysis
                          Feroze B. Mohamed, Ph.D., FASFNR

9:45 – 10:00     Presenting BOLD fMRI Data-Statistical Processing Strategies
                          Devon Middleton, PhD

10:00 – 10:15  Coffee Break

10:15 – 11:00    Clinical Overview of Motor and Language BOLD fMRI Activation, Paradigms and Interpretation

                          Scott H. Faro, MD, FASFNR

11:00 – 11:35    Clinical case review of BOLD fMRI

                          Kiran S. Talekar, MD, MBBS

11:35 – 11:55     Review of Neurovascular Uncoupling (NVU) in BOLD fMRI

                          Jay J. Pillai, M.D., FASFNR

12:00 – 12:45     Lunch & Learn | Sponsored by NordicNeuroLab



12:45 – 2:45.    Practical Exercises on Language Data Processing and Review

Devon Middleton, PhD - step by step lecture
Support Faculty:
Chris Conklin, PhD,
Mahdi Alizadeh, PhD,
Sara Naghizadehkashani, MD, 
Isaiah Ailes, BS, 
Haris I. Sair, M.D., 
Feroze B. Mohamed, PhD, FASFNR

2:45 – 3:00       Coffee Break



3:00 – 3:30        Introduction to Resting state fMRI

                           Haris I. Sair, MD

3:30 – 4:45       Practical Exercise on Resting State Analysis

Haris I. Sair, MD - step by step lecture
Support Faculty:

Devon Middleton, PhD, 
Mahdi Alizadeh, PhD, 
Sara Naghizadehkashani, MD, 
Isaiah Ailes, BS 
Feroze B. Mohamed, PhD, FASFNR 

4:45 – 5:00        Review SPM Processing and Resting State fMRI with Q&A Session

                           All Faculty

5:00                    Workshop Concludes

Educational Objectives Attendees should, at the completion of this workshop, be able to perform the following:


• Preprocessing of BOLD fMRI Data

• Realignment/Coregistration

• Spatial Normalization

• Smoothing Single Subject Analysis

• Model Specification

• Model Estimation

• Visualization of the BOLD fMRI Data Resting State fMRI
• Preprocessing of Resting state data

• Post processing strategies


Hardware/Software Requirements Registrants are required to bring to the workshop their own laptop with a minimum 2G of RAM and 10G of hard disk space. The machines should have preloaded SPM12 and MATLAB software prior to the workshop. DICOM BOLD fMRI practice data sets will be available at the workshop. All registrants will be given instructions on downloading SPM12 and the 15-day free MATLAB license prior to the workshop.

Perfusion Imaging Workshop


Level up your technical skills with ASFNR’s perfusion imaging workshop! This half-day workshop combines didactic lectures with hands-on training to provide attendees with a comprehensive overview on all things perfusion imaging, including: basic principles of perfusion imaging, tips for data acquisition, and advanced post-processing strategies.


Educational Objectives

At the completion of hands-on perfusion workshop, attendees should be able to perform the following:


• Understand basic principles of perfusion imaging and its clinical utility 

• Acquisition and preprocessing of perfusion data

• Processing of perfusion Data

• Post-processing strategies including visualization, interpretation and export of perfusion maps to PACS

• Common errors and limitations of the technique


8:00 - 8:20am       Acute Stroke Perfusion Imaging: A Primer 

                             Max Wintermark


8:20 - 8:40am       DSC T2*Perfusion: How I Do It

                             Amit Desai

8:40 - 9:00am       DCE T1 Perfusion: A primer

                             Robert Young

9:00 - 9:45am       Perfusion Software Presentation


9:45 - 10:00am     Coffee Break

10:00 - 10:45am   Hands-On Portion

                             All attendees

10:45 - 11:15am   DSC T2* Perfusion: How It Increases My Confidence In Brain Tumor Imaging

                             Rajan Jain

11:15 - 12:00pm   Hands-On Portion

                             All attendees


12:00 - 12:30pm   Open session with Olea

bottom of page