A new article in Human Brain Mapping by Benjamin CF et al, Presurgical language fMRI: Mapping of six critical regions investigates how best to identify critical language related brain regions from clinical task-fMRI. The six regions identified by the authors were Broca’s area, Wernicke’s area, Exner’s area, Supplementary Speech area, Angular gyrus [editor note: also […]
An article on biorxiv.org (Lohmann G et al., Inflated False Negative Rates Undermine Reproducibility in Task-Based fMRI) investigates false negative rates in task-fMRI studies (specifically in this paper, motor and emotion tasks from the Human Connectome Project) with various sample sizes. Many task-fMRI studies employ subjects of about 20-40, a range where the authors argue that […]
Knowledge of critical functional brain areas can aid the neurosurgeon in operative planning. However, unique challenges are present in attempting to investigate brain function in the pediatric population using fMRI. Task compliance can be a significant limiting factor. In addition, many of the younger patients may require to be sedated or anesthetized for imaging. […]
Many critical functional brain regions are difficult to identify by anatomy alone, especially when gross distortion is present secondary to brain lesions. In this article, Fisicaro et al from the Memorial Sloan-Kettering Cancer Center demonstrate the difficulty of using anatomy alone to identify the foot motor region in patients with brain tumors. Fisicaro RA […]
The AJNR blog recently posted a book review of the November 2014 Neuroimaging Clinics of North America publication Clinical Applications of Functional MRI, edited by Dr. Jay Pillai: this issue by the Neuroimaging Clinics of North America provides an excellent review of the clinical applications of fMRI. Read the full review here.